The Last Lecture of Randy Pausch (2007)

http://video.google.com/videoplay?docid=-5700431505846055184 (This is the full 1:45 lecture of Randy Pausch, a professor dying of pancreatic cancer).
http://www2.oprah.com/videochannel/videochannel_player.jhtml?video=1178&category=31 (This is a smaller version of his lecture on Oprah. Go to "Professor Randy Pausch's last lecture").

This lecture was so sincere and real. I really enjoyed listening to this man's final words to his class and at some point, his kids, who do not yet know that their father is dying from pancreatic cancer. Very inspirational!
It really helps me to put things in perspective with the nerve damage in my leg too, that causes leg cramps and such. There's a great part about complaining vs. "playing the game harder". And balancing hope and realism. It was just so amazing! I would definitely recommend taking some time to listen.